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Article

Association of prepro-orexin polymorphism with obstructive sleep apnea/hypopnea syndrome.

American journal of otolaryngology - 1 Jan 2000

Chen Weihu, Ye Jingying, Han Demin, Yin Guoping, Wang Boxuan, Zhang Yuhuan

Abstract excerpt

BACKGROUND: Because of the potential role of orexin neuronal circuitry in the regulation of sleep and wakefulness and arousal and breathing, it seems reasonable to speculate that abnormalities in the prepro-orexin gene could be relevant to studies of obstructive sleep apnea/hypopnea syndrome (OSAHS); and it might be a candidate gene in the pathogenesis of OSAHS. OBJECTIVE: The present study investigated whether...

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Identifiers

PMID: 21371780
DOI: 10.1016/j.amjoto.2010.12.005

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