Article
TOX3 mutations in breast cancer.
PloS one - 1 Jan 2013
Jones James Owain, Chin Suet-Feung, Wong-Taylor Li-An, Leaford Donna, Ponder Bruce A J, Caldas Carlos, Maia Ana-Teresa
Abstract excerpt
TOX3 maps to 16q12, a region commonly lost in breast cancers and recently implicated in the risk of developing breast cancer. However, not much is known of the role of TOX3 itself in breast cancer biology. This is the first study to determine the importance of TOX3 mutations in breast cancers. We screened TOX3 for mutations in 133 breast tumours and identified four mutations (three missense, one in-frame deletion...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
