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Article

Mitochondrial DNA Variation of Leber's Hereditary Optic Neuropathy in Western Siberia.

Cells - 4 Dec 2019

Starikovskaya Elena, Shalaurova Sofia, Dryomov Stanislav, Nazhmidenova Azhar, Volodko Natalia, Bychkov Igor, Mazunin Ilia, Sukernik Rem

Abstract excerpt

Our data first represent the variety of Leber's hereditary optic neuropathy (LHON) mutations in Western Siberia. LHON is a disorder caused by pathogenic mutations in mitochondrial DNA (mtDNA), inherited maternally and presents mainly in young adults, predominantly males. Clinically, LHON manifests itself as painless central vision loss, resulting in early onset of disability. The epidemiology of LHON has not been...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Optic Atrophy, Hereditary, Leber

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 31817256
DOI: 10.3390/cells8121574
PMCID: PMC6953113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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