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Whole Mitochondrial Genome Analysis in Serbian Cases of Leber's Hereditary Optic Neuropathy.

Genes - 2 Sept 2020

Dawod Phepy G A, Jancic Jasna, Marjanovic Ana, Brankovic Marija, Jankovic Milena, Samardzic Janko, Potkonjak Dario, Djuric Vesna, Mesaros Sarlota, Novakovic Ivana, Abdel Motaleb Fayda I, Kostic Vladimir S, Nikolic Dejan

Abstract excerpt

Leber's hereditary optic neuropathy (LHON) is a maternally inherited disorder that affects central vision in young adults and is typically associated with mitochondrial DNA (mtDNA) mutations. This study is based on a mutational screening of entire mtDNA in eight Serbian probands clinically and genetically diagnosed with LHON and four of their family members, who are asymptomatic mutation carriers. All obtained...

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Identifiers

PMID: 32887465
DOI: 10.3390/genes11091037
PMCID: PMC7565519

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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