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Article

Autologous mitochondrial microinjection; a strategy to improve the oocyte quality and subsequent reproductive outcome during aging

29 Nov 2019

Abstract excerpt

Along with the decline in oocyte quality, numerous defects such as mitochondrial insufficiency and the increase of mutation and deletion have been reported in oocyte mitochondrial DNA (mtDNA) following aging. Any impairments in oocyte mitochondrial function have negative effects on the reproduction and pregnancy outcome. It has been stated that infertility problems caused by poor quality oocytes in women with in...

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Share to Genetics, Aging, and Longevity in Model Organisms
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PMID: 31798829
DOI: 10.1186/s13578-019-0360-5

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