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Article

Autologous Germline Mitochondrial Energy Transfer (AUGMENT) in Human Assisted Reproduction

17 Nov 2015

Abstract excerpt

Ovarian aging is characterized by a decline in both the total number and overall quality of oocytes, the latter of which has been experimentally tied to mitochondrial dysfunction. Clinical studies in the late 1990s demonstrated that transfer of cytoplasm aspirated from eggs of young female donors into eggs of infertile women at the time of intracytoplasmic sperm injection improved pregnancy success rates....

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PMID: 26574741
DOI: 10.1055/s-0035-1567826

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