Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prenatal Glucocorticoid Exposure Results in Changes in Gene Transcription and DNA Methylation in the Female Juvenile Guinea Pig Hippocampus Across Three Generations

3 Dec 2019

Abstract excerpt

Abstract Synthetic glucocorticoids (sGC) are administered to women at risk for pre-term delivery, to mature the fetal lung and decrease neonatal morbidity. sGC also profoundly affect the fetal brain. The hippocampus expresses high levels of glucocorticoid (GR) and mineralocorticoid receptor (MR), and its development is affected by elevated fetal glucocorticoid levels. Antenatal sGC results in neuroendocrine and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Birth, Development, and Health
Share to Stress Responses and Cortisol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31796763
DOI: 10.1038/s41598-019-54456-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prenatal Glucocorticoid Exposure Results in Changes in Gene Transcription and DNA Methylation in the Female Juvenile Guinea Pig Hippocampus Across Three GenerationsPMID 31796763Read ↗

Prenatal Glucocorticoid Exposure Modifies Endocrine Function and Behaviour for 3 Generations Following Maternal and Paternal TransmissionSemantic proximity Read ↗

Prenatal synthetic glucocorticoid treatment changes DNA methylation states in male organ systems: multigenerational effects.Semantic proximity Read ↗

Antenatal Glucocorticoid Exposure Results in Sex-Specific and Transgenerational Changes in Prefrontal Cortex Gene Transcription that Relate to Behavioural OutcomesSemantic proximity Read ↗

Adult Glucocorticoid Exposure Leads to Transcriptional and DNA Methylation Changes in Nuclear Steroid Receptors in the Hippocampus and Kidney of Mouse Male Offspring1Semantic proximity Read ↗

Prenatal programming of stress responsiveness and behaviours: Progress and perspectivesSemantic proximity Read ↗

Gestational dexamethasone exposure impacts hippocampal excitatory synaptic transmission and learning and memory function with transgenerational effectsSemantic proximity Read ↗

Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylationSemantic proximity Read ↗

Long-Term Effects of the Periconception Period on Embryo Epigenetic Profile and Phenotype: The Role of Stress and How This Effect Is Mediated.Semantic proximity Read ↗

Prenatal maternal stress in rats alters the epigenetic and transcriptomic landscape of the maternal-fetal interface across four generationsSemantic proximity Read ↗

Differential susceptibility of male and female germ cells to glucocorticoid-mediated signalingSemantic proximity Read ↗

Prenatal exposure to dexamethasone in the mouse induces sex‐specific differences in placental gene expressionSemantic proximity Read ↗

Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.