Article
An improved random forest-based computational model for predicting novel miRNA-disease associations.
BMC bioinformatics - 3 Dec 2019
Yao Dengju, Zhan Xiaojuan, Kwoh Chee-Keong
Abstract excerpt
BACKGROUND: A large body of evidence shows that miRNA regulates the expression of its target genes at post-transcriptional level and the dysregulation of miRNA is related to many complex human diseases. Accurately discovering disease-related miRNAs is conductive to the exploring of the pathogenesis and treatment of diseases. However, because of the limitation of time-consuming and expensive experimental methods,...
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