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Article

Prediction of miRNA-disease associations based on PCA and cascade forest.

BMC bioinformatics - 19 Dec 2024

Zhang Chuanlei, Li Yubo, Dong Yinglun, Chen Wei, Yu Changqing

Abstract excerpt

BACKGROUND: As a key non-coding RNA molecule, miRNA profoundly affects gene expression regulation and connects to the pathological processes of several kinds of human diseases. However, conventional experimental methods for validating miRNA-disease associations are laborious. Consequently, the development of efficient and reliable computational prediction models is crucial for the identification and validation of...

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PMID: 39701957
DOI: 10.1186/s12859-024-05999-w
PMCID: PMC11660965

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