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MDSCMF: Matrix Decomposition and Similarity-Constrained Matrix Factorization for miRNA-Disease Association Prediction.

Genes - 6 Jun 2022

Ni Jiancheng, Li Lei, Wang Yutian, Ji Cunmei, Zheng Chunhou

Abstract excerpt

MicroRNAs (miRNAs) are small non-coding RNAs that are related to a number of complicated biological processes, and numerous studies have demonstrated that miRNAs are closely associated with many human diseases. In this study, we present a matrix decomposition and similarity-constrained matrix factorization (MDSCMF) to predict potential miRNA-disease associations. First of all, we utilized a matrix decomposition...

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PMID: 35741782
DOI: 10.3390/genes13061021
PMCID: PMC9223216

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