Article
Identification of the minimal AcMNPV P143 protein region responsible for triggering apoptosis and rRNA degradation of Bombyx mori cells.
Virus research - 15 Jan 2020
Hamajima Rina, Ota Ayaka, Makino Shizuka, Millado Justine Bennette H, Kobayashi Michihiro, Ikeda Motoko
Abstract excerpt
Bombyx mori cells induce antiviral responses including global protein synthesis shutdown, rRNA degradation, and apoptosis upon infection with Autographa californica multiple nucleopolyhedrovirus (AcMNPV). We previously demonstrated that five and six amino acid residues located at positions between 514 and 599 of AcMNPV P143 (Ac-P143) protein are important for induction of apoptosis and rRNA degradation,...
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