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Disruption of Bombyx mori nucleopolyhedrovirus ORF71 (Bm71) results in inefficient budded virus production and decreased virulence in host larvae.

Virus genes - 1 Aug 2012

Zhang Min-Juan, Cheng Ruo-Lin, Lou Yi-Han, Ye Wan-Lu, Zhang Tao, Fan Xiao-Ying, Fan Hai-Wei, Zhang Chuan-Xi

Abstract excerpt

The Bombyx mori nucleopolyhedrovirus (BmNPV) is a baculovirus that selectively infects domestic silkworm. BmNPV ORF71 (Bm71) is not a core set gene in baculovirus and shares 92 % amino acid sequence identity with Autographa californica multinucleocapsid NPV ORF88 (Ac88/cg30). Previously, it has been reported that virus lacking Ac88 had no striking phenotypes in cell lines or host larvae. However, the exact role...

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PMID: 22585339
DOI: 10.1007/s11262-012-0757-2

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