Article
Characterization of Bombyx mori nucleopolyhedrovirus with a deletion of bm118.
Virus research - 1 Aug 2008
Yang Zhang-Nv, Xu Hai-Jun, Park Enoch Y, Zhang Chuan-Xi
Abstract excerpt
Bombyx mori nucleopolyhedrovirus (BmNPV) ORF118 (bm118) is homologous to Autographa californica nucleopolyhedrovirus (AcMNPV) ORF142, one of the core genes existing in all baculovirus genomes sequenced to date, suggesting that Bm118 plays a critical role in viral infection. In this study, the primary role of Bm118 was investigated by using homologous recombination in Escherichia coli to generate a bm118 knockout...
Topics
- Animals
- Bombyx
- Cells, Cultured
- Escherichia coli
- Gene Deletion
- Microscopy, Electron
- Nucleocapsid
- Nucleopolyhedroviruses
- Open Reading Frames
- Phenotype
- Recombination, Genetic
- Transfection
- Viral Proteins
- Virion
