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Article

High- and Low-conditioned Behavioral effects of midazolam in Carioca high- and low-conditioned freezing rats in an ethologically based test.

Neuroscience letters - 10 Jan 2020

Cavaliere Daniele Rodrigues, Maisonnette Silvia, Krahe Thomas E, Landeira-Fernandez J, Cruz Antonio Pedro Mello

Abstract excerpt

The selective breeding of laboratory rodents with different anxiety-related traits is the subject of growing interest. The present study compared the effects of the benzodiazepine midazolam in the elevated plus maze (EPM) test of anxiety in two lines of Wistar rats that were selectively bred in our laboratory for either high or low anxiety-like traits based on a contextual freezing conditioning paradigm. After...

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Identifiers

PMID: 31790719
DOI: 10.1016/j.neulet.2019.134632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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