Article
Interpreting simple STR mixtures using allele peak areas.
Forensic science international - 9 Jan 1998
Gill P, Sparkes R, Pinchin R, Clayton T, Whitaker J, Buckleton J
Abstract excerpt
Although existing statistical models can interpret mixtures qualitatively based upon the alleles present, the use of automated sequencers opens the opportunity to take account of quantitative aspects embodied by the peak area. One step in understanding simple mixtures consisting of just two donors is to estimate the mixture ratio. This is relatively easy to do when four-allele mixtures are evident at a given...
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