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Article

The protein tyrosine kinase SYK regulates the alternative p38 activation in liver during acute liver inflammation.

Scientific reports - 28 Nov 2019

Bang Bo-Ram, Han Kyung Ho, Seo Goo-Young, Croft Michael, Kang Young Jun

Abstract excerpt

Two distinct p38 signaling pathways, classical and alternative, have been identified to regulate inflammatory responses in host defense and disease development. The role of alternative p38 activation in liver inflammation is elusive, while classical p38 signaling in hepatocytes plays a role in regulating the induction of cell death in autoimmune-mediated acute liver injury. In this study, we found that a mutation...

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Source

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Identifiers

PMID: 31780731
DOI: 10.1038/s41598-019-54335-3
PMCID: PMC6882802

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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