Article
Estimation of Homocysteine Level and Methylenetetrahydrofolate Reductase (MTHFR) Gene and Cystathionine B Synthase (CBS) Gene Polymorphisms in Vitiligo Patients.
Skin pharmacology and physiology - 1 Jan 2020
El Tahlawi Samar, Abdel Halim Dalia M, El Hadidi Heba, Fawzy Marwa M, Hegazy Rehab A, Ezzat Marwa, Elgohary Sherin M, Shaker Olfat, Sayed Khadiga S
Abstract excerpt
BACKGROUND: Vitiligo is an acquired, multifactorial disorder of the skin and mucous membranes. An elevated homocysteine level has been described in vitiligo. Methylenetetrahydrofolate reductase (MTHFR) and cystathionine B synthase (CBS) are major determinants of the homocysteine metabolism. OBJECTIVES: Determine serum homocysteine levels in vitiligo patients as well as the association between MTHFR (C677T,...
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