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Article

Genetic polymorphisms in the methylenetetrahydrofolate reductase gene (MTHFR) and risk of vitiligo in Han Chinese populations: a genotype-phenotype correlation study.

The British journal of dermatology - 1 May 2014

Chen J-X, Shi Q, Wang X-W, Guo S, Dai W, Li K, Song P, Wei C, Wang G, Li C-Y, Gao T-W

Abstract excerpt

BACKGROUND: Recent evidence has revealed an elevation of total homocysteine (tHcy) in patients with vitiligo. Methylenetetrahydrofolate reductase (MTHFR) is one of the main enzymes regulating homocysteine (Hcy) metabolism. Thus, polymorphisms of MTHFR could potentially contribute to the development of vitiligo by affecting MTHFR activity and tHcy levels. OBJECTIVES: To evaluate the potential association between...

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Identifiers

PMID: 24472005
DOI: 10.1111/bjd.12845

Genes

MTHFR

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Genetic polymorphisms in the methylenetetrahydrofolate reductase gene (MTHFR) and risk of vitiligo in Han Chinese populations: a genotype-phenotype correlation study.PMID 24472005Read ↗

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