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Article

Novel intermicrobial molecular interaction: Pseudomonas aeruginosa Quinolone Signal (PQS) modulates Aspergillus fumigatus response to iron.

Microbiology (Reading, England) - 1 Jan 2020

Nazik Hasan, Sass Gabriele, Ansari Shajia R, Ertekin Reyhan, Haas Hubertus, Déziel Eric, Stevens David A

Abstract excerpt

Pseudomonas aeruginosa (Pa) and Aspergillus fumigatus (Af), the commonest bacterium and fungus in compromised host airways, compete for iron (Fe). The Pseudomonas quinolone signal (PQS), a Pa quorum sensing molecule, also chelates Fe, and delivers Fe to the Pa cell membrane using Pa siderophores. In models of Af biofilm formation or preformed biofilms, PQS inhibited Af in a low Fe environment. AfΔsidA (mutant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31778108
DOI: 10.1099/mic.0.000858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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