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Inhibition of Zika Virus Replication by Silvestrol

27 Mar 2018

Abstract excerpt

The Zika virus (ZIKV) outbreak in 2016 in South America with specific pathogenic outcomes highlighted the need for new antiviral substances with broad-spectrum activities to react quickly to unexpected outbreaks of emerging viral pathogens. Very recently, the natural compound silvestrol isolated from the plant Aglaia foveolata was found to have very potent antiviral effects against the (−)-strand RNA-virus Ebola...

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PMID: 29584632
DOI: 10.3390/v10040149

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