Article
Structural and functional characterization of three Type B and C chloramphenicol acetyltransferases from Vibrio species
25 Nov 2019
Abstract excerpt
Chloramphenicol acetyltransferases (CATs) were among the first antibiotic resistance enzymes identified and have long been studied as model enzymes for examining plasmid-mediated antibiotic resistance. These enzymes acetylate the antibiotic chloramphenicol, which renders it incapable of inhibiting bacterial protein synthesis. CATs can be classified into different types: Type A CATs are known to be important for...
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