Article
Structural analysis of a putative aminoglycoside N-acetyltransferase from Bacillus anthracis.
Journal of molecular biology - 15 Jul 2011
Klimecka Maria M, Chruszcz Maksymilian, Font Jose, Skarina Tatiana, Shumilin Igor, Onopryienko Olena, Porebski Przemyslaw J, Cymborowski Marcin, Zimmerman Matthew D, Hasseman Jeremy, Glomski Ian J, Lebioda Lukasz, Savchenko Alexei, Edwards Aled, Minor Wladek
Abstract excerpt
For the last decade, worldwide efforts for the treatment of anthrax infection have focused on developing effective vaccines. Patients that are already infected are still treated traditionally using different types of standard antimicrobial agents. The most popular are antibiotics such as tetracyclines and fluoroquinolones. While aminoglycosides appear to be less effective antimicrobial agents than other...
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