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Article

Identification of novel mutations of ovarian cancer-related genes from RNA-sequencing data for Japanese epithelial ovarian cancer patients.

Endocrine journal - 28 Feb 2020

Nagasawa Saya, Ikeda Kazuhiro, Horie-Inoue Kuniko, Sato Sho, Takeda Satoru, Hasegawa Kosei, Inoue Satoshi

Abstract excerpt

Ovarian cancer has the highest mortality rate among gynecological cancers. Gene mutations are involved in the carcinogenesis, metastasis, and therapeutic response in ovarian cancer. However, the variety and proportion of gene mutation is not fully analyzed in Japanese ovarian cancer patients, especially, in those with recurrent tumors. In the present study, RNA-sequencing was performed for 32 clinical ovarian...

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Adenocarcinoma, Clear Cell
beta Catenin
Carcinoma, Endometrioid
Carcinoma, Ovarian Epithelial
Class I Phosphatidylinositol 3-Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasms, Cystic, Mucinous, and Serous

PTEN Phosphohydrolase

Sequence Analysis, RNA

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PMID: 31748433
DOI: 10.1507/endocrj.EJ19-0283

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