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Article

A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation.

Nature communications - 19 Nov 2019

Thestrup M Ilcim, Caviglia Sara, Cayuso Jordi, Heyne Ronja L S, Ahmad Racha, Hofmeister Wolfgang, Satriano Letizia, Wilkinson David G, Andersen Jesper B, Ober Elke A

Abstract excerpt

The hepatopancreatic ductal (HPD) system connects the intrahepatic and intrapancreatic ducts to the intestine and ensures the afferent transport of the bile and pancreatic enzymes. Yet the molecular and cellular mechanisms controlling their differentiation and morphogenesis into a functional ductal system are poorly understood. Here, we characterize HPD system morphogenesis by high-resolution microscopy in...

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Identifiers

PMID: 31745086
DOI: 10.1038/s41467-019-13149-7
PMCID: PMC6864101

Genes

HPD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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