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A network-based approach to identify deregulated pathways and drug effects in metabolic syndrome

18 Nov 2019

Abstract excerpt

Metabolic syndrome is a pathological condition characterized by obesity, hyperglycemia, hypertension, elevated levels of triglycerides and low levels of high-density lipoprotein cholesterol that increase cardiovascular disease risk and type 2 diabetes. Although numerous predisposing genetic risk factors have been identified, the biological mechanisms underlying this complex phenotype are not fully elucidated....

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PMID: 31740673
DOI: 10.1038/s41467-019-13208-z

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