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Article

Interaction between COX-1 and COX-2 Variants Associated with Aspirin Resistance in Chinese Stroke Patients.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Sept 2016

Yi Xingyang, Cheng Wen, Lin Jing, Zhou Qiang, Wang Chun

Abstract excerpt

BACKGROUND: There have been conflicting results for the association between cyclooxygenase (COX) genetic variants and aspirin resistance (AR). The aim of this study was to investigate the association of the COX genetic variants and interaction among these variants with AR in patients with acute ischemic stroke (IS). METHODS: We consecutively enrolled 850 acute IS patients. Platelet aggregation activity was...

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PMID: 27318652
DOI: 10.1016/j.jstrokecerebrovasdis.2016.05.039

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