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Article

Nubp2 is required for cranial neural crest survival in the mouse.

Developmental biology - 15 Feb 2020

DiStasio Andrew, Paulding David, Chaturvedi Praneet, Stottmann Rolf W

Abstract excerpt

The N-ethyl-N-nitrosourea (ENU) ←forward genetic screen is a useful tool for the unbiased discovery of novel mechanisms regulating developmental processes. We recovered the dorothy mutation in such a screen designed to recover recessive mutations affecting craniofacial development in the mouse. Dorothy embryos die prenatally and exhibit many striking phenotypes commonly associated with ciliopathies, including a...

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Identifiers

PMID: 31733190
DOI: 10.1016/j.ydbio.2019.10.039
PMCID: PMC6995770

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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