Article
Biologically Defined or Biologically Informed Traits Are More Heritable Than Clinically Defined Ones: The Case of Oral and Dental Phenotypes.
Advances in experimental medicine and biology - 1 Jan 2019
Agler Cary S, Moss Kevin, Philips Kamaira H, Marchesan Julie T, Simancas-Pallares Miguel, Beck James D, Divaris Kimon
Abstract excerpt
The genetic basis of oral health has long been theorized, but little information exists on the heritable variance in common oral and dental disease traits explained by the human genome. We sought to add to the evidence base of heritability of oral and dental traits using high-density genotype data in a well-characterized community-based cohort of middle-age adults. We used genome-wide association (GWAS) data...
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