Article
Cloning of the genome of a goose parvovirus vaccine strain SYG61v and rescue of infectious virions from recombinant plasmid in embryonated goose eggs.
Journal of virological methods - 1 May 2014
Wang Jianye, Duan Jinkun, Meng Xia, Gong Jiansen, Jiang Zhiwei, Zhu Guoqiang
Abstract excerpt
The SYG61v is an attenuated goose parvovirus (GPV) that has been used as a vaccine strain in China. The genome of SYG61v was sequenced to attempt to identify the genetic basis for the attenuation of this strain. The entire genome consists of 5102 nucleotides (nts), with four nt deletions compared to that of virulent strain B. The inverted terminal repeats (ITR) are 442 nts in length, of which 360 nts form a stem...
Topics
- Animals
- China
- Cloning, Molecular
- DNA, Viral
- Geese
- Molecular Sequence Data
- Mutation
- Parvovirus
- Polymorphism, Genetic
- Sequence Alignment
- Sequence Analysis, DNA
- Vaccines, Attenuated
- Viral Vaccines
- Virion