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Phosphorylation of the Canonical Histone H2A Marks Foci of Damaged DNA in Malaria Parasites

12 Jan 2021

Abstract excerpt

Plasmodium falciparum is the deadliest human parasite that causes malaria when it reaches the bloodstream and begins proliferating inside red blood cells, where the parasites are particularly prone to DNA damage. The molecular mechanisms that allow these pathogens to maintain their genome integrity under such conditions are also the driving force for acquiring genome plasticity that enables them to create...

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PMID: 33441412
DOI: 10.1128/msphere.01131-20

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