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CA8 promotes RCC proliferation and migration though its expression level is lower in tumor compared to adjacent normal tissue

9 Nov 2019

Abstract excerpt

Chemotherapy and radiotherapy are not as successful in the case of renal cell carcinoma (RCC) although some targeted drugs were approved for RCC therapy recently. Analysis of whole genomic data will lead to improvements in understanding RCC and identifying novel anticancer targets. Here, we found the differential mRNA expression and copy number variation (CNV) of Carbonic anhydrase-related protein VIII (CA8) gene...

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PMID: 31715371
DOI: 10.1016/j.biopha.2019.109578

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