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Austalides, Osteoclast Differentiation Inhibitors from a Marine-Derived Strain of the Fungus Penicillium rudallense

11 Nov 2019

Abstract excerpt

Four new meroterpenoids, austalides V–X ( 1 – 3 ) and a farnesylated phthalide derivative ( 4 ), were isolated from the culture of the marine fungus Penicillium rudallense, together with eight known meroterpenoids derivatives ( 5 – 12 ). Their structures, including absolute configurations, were determined by spectroscopic methods. All of the isolated compounds were evaluated for their inhibitory activities on the...

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PMID: 31710223
DOI: 10.1021/acs.jnatprod.9b00690

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