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Article

Megalin: A bridge connecting kidney, the renin-angiotensin system, and atherosclerosis.

Pharmacological research - 1 Jan 2020

Kukida Masayoshi, Sawada Hisashi, Daugherty Alan, Lu Hong S

Abstract excerpt

Megalin is a member of the low-density lipoprotein receptor superfamily. It has been recognized as an endocytic receptor for a large spectrum of ligands. As a consequence, megalin regulates homeostasis of many molecules and affects multiple physiological and pathophysiological functions. The renin-angiotensin system is a hormonal system. A number of studies have reported contributions of the renin-angiotensin...

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Identifiers

PMID: 31707037
DOI: 10.1016/j.phrs.2019.104537
PMCID: PMC6980733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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