Article
Identification of CR43467 encoding a long non-coding RNA as a novel genetic interactant with dFIG4, a CMT-causing gene.
Experimental cell research - 1 Jan 2020
Shimada Saki, Muraoka Yuuka, Ibaraki Kimihide, Takano-Shimizu-Kouno Toshiyuki, Yoshida Hideki, Yamaguchi Masamitsu
Abstract excerpt
The eye imaginal disc-specific knockdown of dFIG4, a Drosophila homolog of FIG4 that is one of the Charcot-Marie-Tooth disease (CMT)-causing genes, induces an aberrant adult compound eye morphology, the so-called rough eye phenotype. We previously performed modifier screening on the dFIG4 knockdown-induced rough eye phenotype and identified several genes, including CR18854, encoding a long non-coding RNA (lncRNA)...
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