Article
Serum exosome inflamma-miRs are surrogate biomarkers for asthma phenotype and severity.
Allergy - 1 Jan 2023
Vázquez-Mera Sara, Martelo-Vidal Laura, Miguéns-Suárez Pablo, Saavedra-Nieves Paula, Arias Pilar, González-Fernández Coral, Mosteiro-Añón Mar, Corbacho-Abelaira María Dolores, Blanco-Aparicio Marina, Méndez-Brea Paula, Salgado Francisco Javier, Nieto-Fontarigo Juan José, González-Barcala Francisco Javier
Abstract excerpt
BACKGROUND: Asthma is a heterogeneous disease with several phenotypes, endotypes and severity degrees, in which different T-cell subpopulations are involved. These cells express specific miRNAs (i.e. inflamma-miRs) that can be released to serum in exosomes after activation and be used as biomarkers of underlying inflammation. Thus, we aim to evaluate specific T-cell miRNA signatures in serum exosomes from...
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