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Target-Induced Cascade Amplification for Homogeneous Virus Detection

8 Nov 2019

Abstract excerpt

Detection of viruses with high sensitivity is critical for the prevention and treatment of the related disease. Two homogeneous target-induced cascade amplification methods were proposed for the detection of enterovirus 71 and coxsackievirus B3. These methods both employ DNAzyme but differ in the way in which the DNAzyme is amplified. In the hybridization chain reaction (HCR)-based strategy, the DNAzyme is...

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Share to Advanced biosensing and bioanalysis techniques
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PMID: 31698906
DOI: 10.1021/acs.analchem.9b03805

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