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Article

The technical risks of human gene editing.

Human reproduction (Oxford, England) - 1 Nov 2019

Davies Benjamin

Abstract excerpt

A recent report from Dr He Jiankui concerning the birth of twin girls harbouring mutations engineered by CRISPR/Cas nucleases has been met with international condemnation. Beside the serious ethical concerns, there are known technical risks associated with CRISPR/Cas gene editing which further raise questions about how these events could have been allowed to occur. Numerous studies have reported unexpected...

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Identifiers

PMID: 31696232
DOI: 10.1093/humrep/dez162
PMCID: PMC6913216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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