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Article

Germ line genome editing in clinics: the approaches, objectives and global society

27 Nov 2015

Abstract excerpt

Genome editing allows for the versatile genetic modification of somatic cells, germ cells and embryos. In particular, CRISPR/Cas9 is worldwide used in biomedical research. Although the first report on Cas9-mediated gene modification in human embryos focused on the prevention of a genetic disease in offspring, it raised profound ethical and social concerns over the safety of subsequent generations and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26615180
DOI: 10.1093/bfgp/elv053

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