Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of a Novel Long Noncoding RNA, lncUSMycN, on N-Myc Expression and Neuroblastoma Progression

1 Jun 2014

Abstract excerpt

BACKGROUND: Patients with neuroblastoma due to the amplification of a 130-kb genomic DNA region containing the MYCN oncogene have poor prognoses. METHODS: Bioinformatics data were used to discover a novel long noncoding RNA, lncUSMycN, at the 130-kb amplicon. RNA-protein pull-down assays were used to identify proteins bound to lncUSMycN RNA. Kaplan-Meier survival analysis, multivariable Cox regression, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Cancer-related molecular mechanisms research
Share to Neuroblastoma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24906397
DOI: 10.1093/jnci/dju113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of a Novel Long Noncoding RNA, lncUSMycN, on N-Myc Expression and Neuroblastoma ProgressionPMID 24906397Read ↗

N-myc and Noncoding RNAs in NeuroblastomaSemantic proximity Read ↗

The Super Enhancer‐Driven Long Noncoding RNA PRKCQ‐AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule CompoundsSemantic proximity Read ↗

NCYM, a Cis-Antisense Gene of MYCN, Encodes a De Novo Evolved Protein That Inhibits GSK3β Resulting in the Stabilization of MYCN in Human NeuroblastomasSemantic proximity Read ↗

The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35Semantic proximity Read ↗

MYCN-targeting miRNAs are predominantly downregulated during MYCN-driven neuroblastoma tumor formationSemantic proximity Read ↗

Co-expression analysis identifies long noncoding RNA <i>SNHG1</i> as a novel predictor for event-free survival in neuroblastomaSemantic proximity Read ↗

Noncoding elements within <i>MYCN</i> mRNA are autonomous drivers of oncogenesis in neuroblastomaSemantic proximity Read ↗

Role of long noncoding RNA in neuroblastoma.Semantic proximity Read ↗

Unveiling MYCN regulatory networks in neuroblastoma via integrative analysis of heterogeneous genomics dataSemantic proximity Read ↗

Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastomaSemantic proximity Read ↗

Next‐generation RNA sequencing reveals differential expression of MYCN target genes and suggests the mTOR pathway as a promising therapy target in <i>MYCN‐</i>amplified neuroblastomaSemantic proximity Read ↗

Role of non-coding RNAs in neuroblastomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.