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Article

Clinical phenotypes predict exacerbations of COPD: the TIE cohort study.

Respiratory medicine - 1 Aug 2025

Ellingsen Jens, Janson Christer, Bröms Kristina, Farkhooy Amir, Hårdstedt Maria, Högman Marieann, Lisspers Karin, Palm Andreas, Ställberg Björn, Malinovschi Andrei

Abstract excerpt

BACKGROUND: In 2017, Burgel and colleagues developed an algorithm to identify clinical phenotypes that predict mortality in COPD. Our study aimed to 1) investigate whether the phenotypes can predict acute exacerbations of COPD (AECOPD) and 2) validate their ability to predict mortality. METHODS: The Tools Identifying Exacerbations (TIE) cohort study recruited participants with spirometry-verified COPD from...

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PMID: 40436119
DOI: 10.1016/j.rmed.2025.108182

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