Article
A Prospective Cohort Study to Assess Obstructive Respiratory Disease Phenotypes and Endotypes in Japan: The TRAIT Study Design.
International journal of chronic obstructive pulmonary disease - 1 Jan 2021
Hizawa Nobuyuki, Fukunaga Koichi, Sugiura Hisatoshi, Nakano Yasutaka, Kato Motokazu, Sugiyama Yutaro, Hanazawa Tomohiro, Kaise Toshihiko, Tal-Singer Ruth, Jones Paul W, Barnes Neil, Compton Chris, Ishii Takeo
Abstract excerpt
Background: Asthma, chronic obstructive pulmonary disease (COPD), and asthma-COPD overlap (ACO) are complex and heterogeneous diseases that share clinical characteristics (phenotypes) and molecular mechanisms (endotypes). Whilst physicians make clinical decisions on diagnostic groups, for some such as ACO there is no commonly accepted criteria. An alternative approach is to evaluate phenotypes and endotypes that...
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