Article
Prediction of exacerbation frequency of AECOPD based on next-generation sequencing and its relationship with imbalance of lung and gut microbiota: a protocol of a prospective cohort study.
BMJ open - 2 Sept 2021
Deng Li, Yan Jiali, Xu Huachong, Huang Chunzhen, Lv Yiwen, Wu Qianxin, Xu Yinji, Chen Xiaoyin
Abstract excerpt
INTRODUCTION: Patients with frequent acute exacerbation phenotype chronic obstructive pulmonary disease (AECOPD) have a higher hospitalisation rate than infrequent exacerbation, the disease progresses quickly and treatment is more difficult. At present, it is impossible to predict patients with COPD with frequent acute exacerbation phenotypes. The composition of the lower respiratory tract flora and the...
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