Article

A Bioinert Hydrogel Framework for Precision 3D Cell Cultures: Advancing Automated High-Content and High-Throughput Drug Screening

2024-08-28

Abstract excerpt

Enhanced drug testing efficiency has driven the prominence of high-content (HC) and high-throughput (HT) screening (HCHTS) in drug discovery and development. However, traditional HCHTS in well-plates often lack complexity of in vivo conditions. 3D cell cultures, like cellular spheroids/organoids, offer a promising alternative by replicating in vivo conditions and improving the reliability of drug responses. Inte...

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Literature Corpus work: 0e51dcf5-121b-5db9-9573-82a2295a6253
DOI: 10.1101/2024.08.27.609940

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