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Article

Universal Testing to Identify Lynch Syndrome Among Women With Newly Diagnosed Endometrial Carcinoma.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC - 1 Feb 2020

Cameron Anna, Chiarella-Redfern Helene, Chu Pamela, Perrier Renee, Duggan Máire A

Abstract excerpt

BACKGROUND: Lynch syndrome (LS) is an autosomal dominant cancer syndrome caused by a germline mutation in the mismatch repair (MMR) genes. Protocols based on immunohistochemical expression of MMR proteins in cancer are used to identify patients with LS. METHODS: The universal LS screening protocol of the Tom Baker Cancer Centre (Calgary, AB) of all patients diagnosed between April 1, 2013 and April 1, 2015 with...

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Identifiers

PMID: 31679916
DOI: 10.1016/j.jogc.2019.06.018

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Universal Testing to Identify Lynch Syndrome Among Women With Newly Diagnosed Endometrial Carcinoma.PMID 31679916Read ↗

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Universal Screening for Mismatch-Repair Deficiency in Endometrial Cancers to Identify Patients With Lynch Syndrome and Lynch-like SyndromeSemantic proximity Read ↗

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Lynch Syndrome Screening Should Be Considered for All Patients With Newly Diagnosed Endometrial CancerSemantic proximity Read ↗

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