Article
Evolutionary adaptation of Aspergillus niger for increased ferulic acid tolerance.
Journal of applied microbiology - 1 Mar 2020
Lubbers R J M, Liwanag A J, Peng M, Dilokpimol A, Benoit-Gelber I, de Vries R P
Abstract excerpt
AIMS: To create an Aspergillus niger mutant with increased tolerance against ferulic acid using evolutionary adaptation. METHODS AND RESULTS: Evolutionary adaptation of A. niger N402 was performed by consecutive growth on increasing concentrations of ferulic acid in the presence of 25 mmol l-1 d-fructose, starting from 0·5 mmol l-1 and ending with 5 mmol l-1 ferulic acid. The A. niger mutant obtained after six...
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