Article
Tetraploid Partial Hydatidiform Moles: Molecular Genotyping and Determination of Parental Contributions.
The Journal of molecular diagnostics : JMD - 1 Jan 2020
Bynum Jennifer, Batista Denise, Xian Rena, Xing Deyin, Eshleman James R, Ronnett Brigitte M, Zheng Gang
Abstract excerpt
DNA genotyping studies have established that most partial hydatidiform moles (PHMs) are diandric dispermic triploid conceptions. Rare triandric tetraploid PHMs have been described, but genotyping cannot determine the manner in which three paternal chromosome complements are derived (one sperm with triplication, two sperm with one duplication, three different sperm, or one diploid and one haploid sperm). In a...
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