Article
Tetraploidy in hydatidiform moles.
Human reproduction (Oxford, England) - 1 Jul 2013
Sundvall Linda, Lund Helle, Niemann Isa, Jensen Uffe Birk, Bolund Lars, Sunde Lone
Abstract excerpt
STUDY QUESTION: How does tetraploidy develop in hydatidiform moles (HMs), and what is the frequency of the different origins? SUMMARY ANSWER: Most molar pregnancies with tetraploid cells appear to be produced by somatic endoreduplications, while a minority originate from a tetraploid zygote. The frequency of zygotic tetraploidy was estimated to be 0.7%. WHAT IS KNOWN ALREADY: The parental origin of the genome in...
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