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Article

DNA methylation in repeat negative prostate biopsies as a marker of missed prostate cancer.

Clinical epigenetics - 30 Oct 2019

Fiano Valentina, Zugna Daniela, Grasso Chiara, Trevisan Morena, Delsedime Luisa, Molinaro Luca, Cassoni Paola, Papotti Mauro, Merletti Franco, Akre Olof, Pettersson Andreas, De Marco Laura, Richiardi Lorenzo

Abstract excerpt

BACKGROUND: Men often undergo repeat prostate biopsies because of suspicion of missed cancer. We assessed if (i) methylation of selected genes in prostate tissue vary with aging and (ii) methylation alterations in repeat biopsies predict missed prostate cancer. METHODS: We conducted a case-control study among men who underwent at least two negative prostate biopsies followed by a sampling either positive (cases...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31666119
DOI: 10.1186/s13148-019-0746-6
PMCID: PMC6820908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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