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Complete nontuberculous mycobacteria whole genomes using an optimized DNA extraction protocol for long-read sequencing

30 Oct 2019

Abstract excerpt

BACKGROUND: Nontuberculous mycobacteria (NTM) are a major cause of pulmonary and systemic disease in at-risk populations. Gaps in knowledge about transmission patterns, evolution, and pathogenicity during infection have prompted a recent surge in genomic NTM research. Increased availability and affordability of whole genome sequencing (WGS) techniques provide new opportunities to sequence and construct complete...

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PMID: 31666009
DOI: 10.1186/s12864-019-6134-y

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