Article
A scalable, efficient, and safe method to prepare high quality DNA from mycobacteria and other challenging cells
4 Feb 2020
Abstract excerpt
The rapid development in sequencing technology is creating an increase in demand for largely intact DNA as starting material as very long strands of DNA are sequenced directly to generate reads that are thousands of bases long. Organisms with thick cell walls are difficult to lyse, often impacting both DNA recovery and quality. Consequently, most mycobacterial DNA extraction methods require bead-beating steps or...
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